제약 및 생물의학 충전 라인

No matter how good your product is, it won’t work well if you use the wrong pharmaceutical filling machine or packaging materials. VKPAK offers a wide range of packaging solutions for powders, liquids and other pharmaceutical products. We supply auger, vibratory, and piston filling machines. Each of them ensures your items are packaged quickly and accurately.

We know each customer’s needs are different. That’s why we’ll work closely with you to create the specific pharma packaging solutions you need. We’ll help you choose the right pharmaceutical filling machine to ensure your goods are protected from moisture, light, or gases, as required.

Our complete pharmaceutical and biomedical filling lines are designed to fill anything from peroxide and e-liquid to liquid vitamins and everything in-between. Our packaging lines are designed to fill with efficiency and are manufactured to minimize downtime. It is time to start your project today by picking a line below!

This automatic e-liquid filling line comes with everything you need to get your e-liquid bottling line up and running. It is designed to bottle up to 40 bottles per minute.

This automatic liquid vitamin filling line comes with everything you need to get your liquid vitamin bottling line up and running. It is designed to bottle 40-50 bottles per minute.

Pharmaceutical filling lines expedite the modern pharmaceutical manufacturing process. Syringe filling equipment is used for large scale filling and ensures sterility and dispensing of correct volume. Vial filling equipment can fill hundreds of vials per minute while securing against product loss and inconsistent volume. Pharmaceutical checkweighers are used to sort out broken or otherwise-flawed tablets, and they ensure that the final product meets quality standards before packaging. A variety of pharmaceutical filling equipment streamlines the pharmaceutical manufacturing process.

The Roles of Pharmaceutical Filling Equipment

Although these products are separate and distinct industries by themselves, they do all share the same characteristics insofar as the type of filling machine that is suitable. These products almost always involve small, accurate fill volumes into small containers that are sometimes difficult to handle.

이 논의에는 제약 산업에서 사용되는 충진기가 포함되지만, 건강기능식품, 생물의학 및 진단용 특수 화학 산업보다 제약 충진에 대한 적용 요건이 훨씬 더 엄격한 경우가 많습니다. 많은 제약 응용 분야에서는 충진 측면뿐만 아니라 용기 밀봉 및 취급을 포함한 포장 공정의 모든 요소에 대한 완전하고 규제적이며 검증된 제어가 필요합니다. 이를 위해서는 단순한 독립형 충진기 이상의 것이 필요합니다. "모노블록"이라고 하는 다기능 기계는 필요한 모든 기능을 수행할 수 있습니다. 반면, 용기를 더 쉽게 취급할 수 있는 경우에는 더 간단한 독립형 연동 충진기로 생물의학, 진단, 건강기능식품 산업의 대부분의 응용 분야를 처리할 수 있으며, 제약 산업으로의 일부 전환도 가능합니다. 대부분의 경우 이러한 제품에 사용되는 액체 공급 시스템은 연동 펌프, 소형 피스톤 또는 마이크로 용적 펌프입니다. 모든 경우에 디지털로 인코딩된 서보 드라이브를 사용하여 시스템의 정확성과 문서화를 향상시킵니다.

Biomedical, nutraceutical and diagnostic products are produced in small size glass and plastic vials. Normally these container sizes are not as small as some of the doses in pharmaceutical products. This makes these products suitable for conventional conveyor fed filling lines. Therefore, a standalone peristaltic machine is Ideal for these products because of the high accuracy required of these small fill sizes and also because many of these products have a high economic value per volume. Another very important feature of this delivery system is the fact that cross contamination of different products is virtually impossible if adherence to good manufacturing practices is followed.

Cross contamination is avoided in a peristaltic filling machine because the only thing that touches the liquid is the peristaltic tubing itself. This tubing is composed of surgical grade silicone or other inert specialty polymer materials. This tubing is inexpensive and can be easily cleaned, dedicated to a particular liquid, or simply thrown away after use. It can also be sterilized in an autoclave for reuse. The size of tubing chosen in this machine depends on the fill size and accuracy required. The smaller the diameter of tubing used, the higher the accuracy but the slower the fill rate. This explains why this machine is best utilized on small fills where high accuracy is needed. Large fill sizes greater than 1 liter are typically not filled on this type of machine because the fill cycle time can be lengthy. But for a typical fill size of 5 to 100 ml, again this is the ideal machine.

When the containers are so small as to not be handled manually or on a conveyor delivery system, a standalone peristaltic system is not practical. In this case, a peristaltic delivery system is installed on a mechanical platform better suited to physical container control. This system is called a monoblock system and typically features all liquid packaging operations in one platform.

Automatic monoblock fill cap plug systems are typically small footprint platforms designed to handle small or inherently unstable containers that cannot be practically filled and closed on a intermittent straight line filling machine. These platforms are typically used for filling pharmaceutical and biomedical high purity products where the requirements for cleanliness are an extreme and/or where verifiable control and validation of all packaging parameters is required by the FDA or other regulatory agencies. These filling machine systems are usually found in controlled atmospheres i.e. “clean rooms” where the possibility of particle contamination is practically eliminated. Some monoblock systems incorporate their own laminar flow, hepa-filtered enclosures to isolate the containers in a controlled atmosphere thereby controlling contamination potential. VKPAK has built these capital machines with great success.

Small precise fills of controlled pharmaceuticals, injectables and diagnostic reagents followed by special closures such as stoppers, aluminum crimp seals, plugs and screw caps with precise application torque are accomplished on this platform. It should be noted that there are also some industrial chemical applications filling into larger bulk containers that have the same rigorous cleanliness requirements as pharmaceuticals. An example of this would be high purity solvents used in semiconductor manufacturing. Monoblock machines used in industrial applications like this are much larger in size than a typical pharmaceutical application.